产品
编 号:F361903
分子式:C22H23ClN4
分子量:378.9
产品类型
结构图
CAS No: 4569-86-2
联系客服
产品详情
生物活性:
Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy).
体外研究:
Methylene Violet 3RAX shows antitumor activity by cutting off DNA strands in tumour cell.Methylene Violet 3RAX (0-400 μM) significantly enhances cleavage of DNA with over 60% photocleavage activity towards DNA at 300 μM.