产品
编 号：F360776
分子式：C13H8Cl2N4S2
分子量：355.27
分子式：C13H8Cl2N4S2
分子量：355.27
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
1020
In-stock
1mg
286
In-stock
5mg
917
In-stock
10mg
1308
In-stock
50mg
4711
In-stock
100mg
8922
In-stock
结构图
CAS No: 448947-81-7
产品详情
生物活性：
Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation.
体外研究：
Yoda1 (0-6 μM，5 min) 诱导不依赖于 Piezo1 的 Akt 和 ERK1/2 的激活。Yoda1 (1.5 μM，5 min) 抑制 Rac1 的激活。
Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation.
体外研究：
Yoda1 (0-6 μM，5 min) 诱导不依赖于 Piezo1 的 Akt 和 ERK1/2 的激活。Yoda1 (1.5 μM，5 min) 抑制 Rac1 的激活。
产品资料
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