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编 号：F360183
分子式：C23H24F2N2O7S
分子量：510.51
分子式：C23H24F2N2O7S
分子量：510.51
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CAS No: 445441-27-0
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生物活性：
SGS518 oxalate is a selective 5-HT6R antagonist. SGS518 oxalate can be used for the research of cognitive impairments such as amnesia, anxiety and depression, and it is effective in protecting mouse retina at high doses
体内研究：
SGS518 oxalate (30 mg/kg; i.p. for 30 min) protects Abca4–/–Rdh8 sup>–/– mouse retinas from light-induced damage.Animal Model:Abca4–/–Rdh8 sup>–/–mice are exposed at white light
Dosage:30 mg/kg
Administration:I.p. injection for 30 minutes
Result:A marked preservation of the photoreceptor layer.Reduced formation of autofluorescent spots in mice.Protected retinal morphology.
SGS518 oxalate is a selective 5-HT6R antagonist. SGS518 oxalate can be used for the research of cognitive impairments such as amnesia, anxiety and depression, and it is effective in protecting mouse retina at high doses
体内研究：
SGS518 oxalate (30 mg/kg; i.p. for 30 min) protects Abca4–/–Rdh8 sup>–/– mouse retinas from light-induced damage.Animal Model:Abca4–/–Rdh8 sup>–/–mice are exposed at white light
Dosage:30 mg/kg
Administration:I.p. injection for 30 minutes
Result:A marked preservation of the photoreceptor layer.Reduced formation of autofluorescent spots in mice.Protected retinal morphology.
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