产品
编 号：F359386
分子式：C18H17FN2O
分子量：296.34
分子式：C18H17FN2O
分子量：296.34
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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50mg
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结构图
CAS No: 442633-00-3
产品详情
生物活性：
CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 μM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation.
体外研究：
CK-666 (100 μM) significantly reduces the number of filopodia on the cell surface of treated trabecular meshwork (TM) cells as well as reduces the length of those filopodia that are present.
CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 μM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation.
体外研究：
CK-666 (100 μM) significantly reduces the number of filopodia on the cell surface of treated trabecular meshwork (TM) cells as well as reduces the length of those filopodia that are present.
产品资料
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