产品
编 号：F358586
分子式：C24H25ClFN5O3
分子量：485.94
分子式：C24H25ClFN5O3
分子量：485.94
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
141
In-stock
250mg
282
In-stock
结构图
CAS No: 439081-18-2
产品详情
生物活性：
(E/Z)-Afatinib ((E/Z)-BIBW 2992) is the mixture of (E)-Afatinib and (Z)-Afatinib. Afatinib (HY-10261) is an irreversible inhibitor of EGFR, by irreversibly binding to their ATP binding site to block activation of EGFR, HER2, HER4, and EGFRvIII. Afatinib used in co-administration with Temozolomide (HY-17364), potently targeting to EGFRvIII-cMet signaling in glioblastoma cells.
体外研究：
有效、不可逆的 Her2/ErbB 2 和 EGFR 激酶抑制剂
(E/Z)-Afatinib ((E/Z)-BIBW 2992) is the mixture of (E)-Afatinib and (Z)-Afatinib. Afatinib (HY-10261) is an irreversible inhibitor of EGFR, by irreversibly binding to their ATP binding site to block activation of EGFR, HER2, HER4, and EGFRvIII. Afatinib used in co-administration with Temozolomide (HY-17364), potently targeting to EGFRvIII-cMet signaling in glioblastoma cells.
体外研究：
有效、不可逆的 Her2/ErbB 2 和 EGFR 激酶抑制剂
产品资料
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