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编 号:F357678
分子式:C69H91N19O16S2
分子量:1506.71
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结构图
CAS No: 436083-30-6
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JKC363, a selective melanocortin MC4 receptor antagonist, has a 90-fold higher affinity at the MC4 receptor (IC50=0.5 nM) than at the MC3 receptor (44.9 nM). JKC-363 blocks the stimulatory effect of α-MSH on TRH release. Anti-hyperalgesic effect.