产品
编 号:F355612
分子式:C23H27N3O4
分子量:409.48
产品类型
结构图
CAS No: 425671-29-0
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产品详情
生物活性:
LY518674 is a potent, selective PPARα agonist, with an EC50 of 42 nM for human PPARα. LY518674 reduces triglycerides in and increased HDL-C and is used for the treatment of atherosclerosis.
体内研究:
LY518674 reduces triglycerides and increased HDL-C in vivo.LY518674 substantially increases apolipoprotein A-I (apoA-I) turnover without major impact on steady-state levels of apoA-I or high-density lipoprotein-cholesterol (HDL-C) .