产品
编 号：F355503
分子式：C19H17N6NaO6S2
分子量：512.49
分子式：C19H17N6NaO6S2
分子量：512.49
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CAS No: 42540-40-9
产品详情
生物活性：
Cefamandole nafate (Cefamandole formate sodium) is a second-generation broad-spectrum cephalosporin antibiotic.
体内研究：
The toxicity of Cefamandole nafate administered iv Is studied in rats receiving doses of 250-1,000 mg/kgfive days per week for one month.After the administration of Cefamandole nafate for one month, there are no treatment-related adverse effects on growth, food consumption, clinical chemistry, hematology, or organ weights.
体外研究：
Cefamandole nafate is shown to be rapidly converted to cefamandole in bacteriological media, with a half-life of less than 1 h at a pH of 7.0 or above. At pH 6.0, in log-phase inhibition experiments, however, Cefamandole nafate is more stable, allowing delineation of the activity between cefamandole and cefamandole nafate.
Cefamandole nafate (Cefamandole formate sodium) is a second-generation broad-spectrum cephalosporin antibiotic.
体内研究：
The toxicity of Cefamandole nafate administered iv Is studied in rats receiving doses of 250-1,000 mg/kgfive days per week for one month.After the administration of Cefamandole nafate for one month, there are no treatment-related adverse effects on growth, food consumption, clinical chemistry, hematology, or organ weights.
体外研究：
Cefamandole nafate is shown to be rapidly converted to cefamandole in bacteriological media, with a half-life of less than 1 h at a pH of 7.0 or above. At pH 6.0, in log-phase inhibition experiments, however, Cefamandole nafate is more stable, allowing delineation of the activity between cefamandole and cefamandole nafate.
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