产品
编 号：F354611
分子式：C5H7ClN2O3
分子量：178.57
分子式：C5H7ClN2O3
分子量：178.57
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CAS No: 42228-92-2
产品详情
生物活性：
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.
体内研究：
Acivicin (AT-125; 5 mg/kg; IP; twice weekly) reduces urinary γ-GT by 70-78%.Animal Model:Male pigmented Long-Evans rats weighed between 250 g and 300 g exposed to Toluene
Dosage:5 mg/kg
Administration:IP; twice weekly (monday and wednesday)
Result:Reduced urinary γ-GT by 70-78%.
体外研究：
Acivicin (AT-125; 0.1-50 μM; 5 days) has an IC50 of 0.7 μM in human HepG2 cells.
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.
体内研究：
Acivicin (AT-125; 5 mg/kg; IP; twice weekly) reduces urinary γ-GT by 70-78%.Animal Model:Male pigmented Long-Evans rats weighed between 250 g and 300 g exposed to Toluene
Dosage:5 mg/kg
Administration:IP; twice weekly (monday and wednesday)
Result:Reduced urinary γ-GT by 70-78%.
体外研究：
Acivicin (AT-125; 0.1-50 μM; 5 days) has an IC50 of 0.7 μM in human HepG2 cells.
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