产品
编 号：F354254
分子式：C21H12N2O7
分子量：404.33
分子式：C21H12N2O7
分子量：404.33
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 420841-84-5
产品详情
生物活性：
H2L 5765834 is an antagonist of lysophosphatidic acid receptors LPA1, LPA3, and LPA5, with IC50s of 94, 752, and 463 nM respectively.
体内研究：
H2L 5765834 (20 mg/kg; i.p.) could not affect the LPA-induced decrease of alanine transaminase (ALT) in the acetaminophen (APAP) overdose-induced acute liver injury model.
体外研究：
H2L 5765834 displays no effect on LPA2 or LPA4 receptors.H2L 5765834 inhibits LPA-induced platelet shape change with an IC50 of 13.73±2.52 μM.
H2L 5765834 is an antagonist of lysophosphatidic acid receptors LPA1, LPA3, and LPA5, with IC50s of 94, 752, and 463 nM respectively.
体内研究：
H2L 5765834 (20 mg/kg; i.p.) could not affect the LPA-induced decrease of alanine transaminase (ALT) in the acetaminophen (APAP) overdose-induced acute liver injury model.
体外研究：
H2L 5765834 displays no effect on LPA2 or LPA4 receptors.H2L 5765834 inhibits LPA-induced platelet shape change with an IC50 of 13.73±2.52 μM.
产品资料
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