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编 号:F353040
分子式:C20H32O5
分子量:352.47
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1mg
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5mg
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生物活性:
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances. PGD2 plays a protective role by suppressing inflammation.

体内研究:
Prostaglandin D2 (PGD2; infused into the lateral ventricle; 5-50 pmol/min; for 6 hours between 20:00 and 2:00) induces sleep-wake profiles in A2AR KO mice.Animal Model:Male WT and A2AR KO mice of the inbred C57BL/6 strain (weighing 23-27 g, 11-13 weeks old)
Dosage:5, 10, 20, or 50 pmol/min
Administration:Infused into the lateral ventricle; for 6 hours between 20:00 and 2:00
Result:Induced sleep-wake profiles.
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