产品
编 号：F350385
分子式：C13H17ClN2O
分子量：252.74
分子式：C13H17ClN2O
分子量：252.74
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 40600-13-3
产品详情
生物活性：
Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full?α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM).
体内研究：
Cirazoline hydrochloride (drinking water; 40 μM; 9 month) exhibits significantly decreased immobility in the TST and enhances neurogenesis in the mouse.Animal Model:B6/CBA mice
Dosage:40 μM
Administration:Drinking water; 40 μM; 9 month
Result:Reversed antidepressant-like phenotype of CAM α1A-AR Mice .
体外研究：
Cirazoline hydrochloride (5-10 μM; 24 hours) does not alter GIC survival and counteracted only poorly prazosin‐induced GIC death.
Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full?α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM).
体内研究：
Cirazoline hydrochloride (drinking water; 40 μM; 9 month) exhibits significantly decreased immobility in the TST and enhances neurogenesis in the mouse.Animal Model:B6/CBA mice
Dosage:40 μM
Administration:Drinking water; 40 μM; 9 month
Result:Reversed antidepressant-like phenotype of CAM α1A-AR Mice .
体外研究：
Cirazoline hydrochloride (5-10 μM; 24 hours) does not alter GIC survival and counteracted only poorly prazosin‐induced GIC death.
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