产品
编 号:F350343
分子式:C17H27NO9
分子量:389.4
产品类型
结构图
CAS No: 40592-88-9
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产品详情
生物活性:
TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis.
体内研究:
TLR4-IN-C34 (C34, 1 mg/kg, orally daily) could attenuate NEC severity and demonstrates a marked preservation of the intestinal mucosa.Animal Model:Experimental NEC induced in 7-8 day old mice.
Dosage:1 mg/kg.
Administration:Orally every morning.
Result:Attenuated intestinal inflammation.