产品
编 号：F039792
分子式：C6H15ClN4O2
分子量：210.66
分子式：C6H15ClN4O2
分子量：210.66
产品类型
规格
价格
是否有货
500mg
280
In-stock
1g
360
In-stock
5g
640
In-stock
结构图
CAS No: 1119-34-2
产品详情
生物活性：
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis.
体内研究：
L-Arginine 已经被广泛接受用来诱导实验性急性胰腺炎的模型。L-Arginine 诱导模型剂量参考：（1）模式动物：雄性Wistar白化大鼠急性胰腺炎：单次腹腔注射 L-Arginine 500 mg /100 g体重（2）模式动物：雄性 ICR 小鼠急性胰腺炎：分 2 次隔 1 小时腹腔注射 2.25g/kg 体重的 L-ArginineL-Arginine 的溶解方法参考：将 L-Arginine 粉末溶解于 0.9% 生理盐水中，用 5 N 盐酸调节 pH 至 7，制得 L-Arginine 溶液。
体外研究：
Arginine is an α-amino acid. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice.
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis.
体内研究：
L-Arginine 已经被广泛接受用来诱导实验性急性胰腺炎的模型。L-Arginine 诱导模型剂量参考：（1）模式动物：雄性Wistar白化大鼠急性胰腺炎：单次腹腔注射 L-Arginine 500 mg /100 g体重（2）模式动物：雄性 ICR 小鼠急性胰腺炎：分 2 次隔 1 小时腹腔注射 2.25g/kg 体重的 L-ArginineL-Arginine 的溶解方法参考：将 L-Arginine 粉末溶解于 0.9% 生理盐水中，用 5 N 盐酸调节 pH 至 7，制得 L-Arginine 溶液。
体外研究：
Arginine is an α-amino acid. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice.
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