产品
编 号:F347076
分子式:C13H17NO2
分子量:219.28
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10mM*1mL in DMSO
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5mg
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10mg
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生物活性:
Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory agent (NSAID) of the phenylpropionic acid class. Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both secretory phospholipase A2 (sPLA2) and COX-2.

体内研究:
Alminoprofen (100-300 mg/kg; p.o.) exerts an anti-inflammatory activity.Animal Model:Groups of Wistar Rats (Oedema of the paw)
Dosage:100 mg/kg
Administration:P.o.
Result:Exerted a statistically significant dose-dependent antagonist action lasting throughout the 2-hr observation period.

体外研究:
Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both sPLA2 but also COX-2. Alminoprofen (from 0 to 50 μM) induces a dose-related inhibitory response on thelevels of PGE2 formed by the CRL-1517 cell line.
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