产品
编 号:F344711
分子式:C16H19N3O4S
分子量:349.4
产品类型
结构图
CAS No: 38821-53-3
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产品详情
生物活性:
Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK.
体内研究:
Cephradine (25 mg/kg; s.c.; 11 days) reduces the bacterial density and counts in the abscesses.Animal Model:Nondiabetic mice
Dosage:25 mg/kg
Administration:S.c.; 11 days
Result:Reduced the bacterial density and counts in the abscesses.
体外研究:
Cephradine (0~8 μg/mL; 12 hours) makes bacterial viability rapidly increased at antibiotic concentrations below the MIC (minimum inhibitory concentration) of 0.70 μg/mL at both pH 7.4 and pH 5.5.