产品
编 号：F344302
分子式：C25H47NO4
分子量：425.64
分子式：C25H47NO4
分子量：425.64
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 38677-66-6
产品详情
生物活性：
Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation.
体内研究：
Oleoylcarnitine (AC18:1) accumulates markedly in obesity-driven HCC tissues of mice.Animal Model:MUP-uPA and PIK3CA Tg mice.
Dosage:
Administration:High-fat diet (HFD) for mice
Result:Accumulated in HCC tissues and in the serum of HFD-fed mice.
体外研究：
Oleoylcarnitine (AC18:1) (5, 25, 50 μM; 24, 48 hours) concentration significantly increases in the Dih10 cells with stable CPT2 knock down.Oleoylcarnitine (5 μM, 24 hours) contributes directly to hepatocarcinogenesis by conferring stem cell properties to cancer cells through STAT3 activation.
Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation.
体内研究：
Oleoylcarnitine (AC18:1) accumulates markedly in obesity-driven HCC tissues of mice.Animal Model:MUP-uPA and PIK3CA Tg mice.
Dosage:
Administration:High-fat diet (HFD) for mice
Result:Accumulated in HCC tissues and in the serum of HFD-fed mice.
体外研究：
Oleoylcarnitine (AC18:1) (5, 25, 50 μM; 24, 48 hours) concentration significantly increases in the Dih10 cells with stable CPT2 knock down.Oleoylcarnitine (5 μM, 24 hours) contributes directly to hepatocarcinogenesis by conferring stem cell properties to cancer cells through STAT3 activation.
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