产品
编 号:F343418
分子式:C18H29NO2
分子量:291.43
产品类型
结构图
CAS No: 38363-41-6
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产品详情
生物活性:
(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.
体外研究:
(+)-penbutolol on the [Ca2+]i-increase induced by LPC is concentration-dependent.(+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10-6 M, 5×10-6 M and 10-5 M, respectively).