产品
编 号:F342917
分子式:C9H15N5O
分子量:209.25
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500mg
280
In-stock
1g
360
In-stock
5g
864
In-stock
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生物活性:
Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM.

体内研究:
Minoxidil (0.01 mmoL/kg body weight; intraperitoneal injection; for 3.5 hours; fisher 344 rats) treatment inhibits carrageenan-induced rat paw oedema with an inhibitory potency (49%).Animal Model:Fisher 344 rats (150-200 g) with oedema
Dosage:0.01 mmol/kg body weight
Administration:Intraperitoneal injection; for 3.5 hours
Result:Inhibition of the carrageenin-induced oedema.

体外研究:
Minoxidil (1-00 μM; 24 hours; RAMEC cells) treatment shows very low cytotoxicities in the whole area of concentrations examined? (from 1 μM to 100 μM).
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