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编 号：F342414
分子式：C26H30N6O3
分子量：474.55
分子式：C26H30N6O3
分子量：474.55
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CAS No: 381231-18-1
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生物活性：
Macimorelin (EP-1572), a GH secretagogue, is an orally active GHSR agonist. Macimorelin stimulates GH release. Macimorelin can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS).
体内研究：
Macimorelin (5 mg/kg, i.p. twice daily for 2 weeks) decreases the number and duration of seizures in IHKA mouse model. Animal Model:Intrahippocampal kainic acid (IHKA) mouse model
Dosage:5 mg/kg
Administration:Intraperitoneal injection (i.p.), twice daily for 2 weeks.
Result:Significantly decreased the number and duration of seizures during the treatment period, but had no antiepileptogenic or disease-modifying effect.
Macimorelin (EP-1572), a GH secretagogue, is an orally active GHSR agonist. Macimorelin stimulates GH release. Macimorelin can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS).
体内研究：
Macimorelin (5 mg/kg, i.p. twice daily for 2 weeks) decreases the number and duration of seizures in IHKA mouse model. Animal Model:Intrahippocampal kainic acid (IHKA) mouse model
Dosage:5 mg/kg
Administration:Intraperitoneal injection (i.p.), twice daily for 2 weeks.
Result:Significantly decreased the number and duration of seizures during the treatment period, but had no antiepileptogenic or disease-modifying effect.
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