产品
编 号:F342269
分子式:C15H17ClN2O2
分子量:292.76
产品类型
结构图
CAS No: 38083-17-9
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生物活性:
Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450.
体外研究:
Climbazole (20?μM; 48?hours) significantly decreases exosome secretion in aggressive prostate cancer (PCa) cells.Climbazole (20?μM) significantly inhibits the protein concentration of Alix, and Rab27a but not nSMase2.Climbazole is a potent inhibitor of exosome biogenesis and/or secretion.