产品
编 号:F341879
分子式:C40H47N11O6
分子量:777.87
产品类型
结构图
CAS No: 380221-63-6
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产品详情
生物活性:
UK-432097 is a highly potent and selective A2AAR agonist with a pKi of 8.4 for human A2AAR. UK-432097 has anti-inflammatory and anti-aggregatory properties. UK-432097 has the potential for COPD (Chronic Obstructive Pulmonary Disease) research.
体外研究:
UK-432097 has an EC50 value of 0.66 nM using CHO cells expressing human WT A50AR. UK-432097 (0.01, 0.1, 1, 10, 100, 1000 nM; pretreated for 2 hours) significantly increases cAMP accumulation in CHO-A2A cells.