产品
编 号：F341421
分子式：C13H12O3
分子量：216.23
分子式：C13H12O3
分子量：216.23
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
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结构图
CAS No: 3785-24-8
产品详情
生物活性：
Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities.
体内研究：
Nepodin (Musizin) (orally administration; 2-10 mg/kg; 4 weeks) improves the impaired glucose tolerance of db/db mice, also decreases an increase in plasma insulin concentration of db/db mice in a dose-dependent manner.Animal Model:C57BL/KsJ-db/db mice
Dosage:2 mg/kg; 10 mg/kg
Administration:Orally administration; 2-10 mg/kg; 4 weeks
Result:Had antihyperglycemic potential and improved insulin resistance.
体外研究：
Nepodin (Musizin) exhibits significant IC50 values that are 0.74 and 0.79 μg/ml against P. falciparum chloroquine-sensitive (3D7) and P. falciparum chloroquine-resistant (S20), respectively.
Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities.
体内研究：
Nepodin (Musizin) (orally administration; 2-10 mg/kg; 4 weeks) improves the impaired glucose tolerance of db/db mice, also decreases an increase in plasma insulin concentration of db/db mice in a dose-dependent manner.Animal Model:C57BL/KsJ-db/db mice
Dosage:2 mg/kg; 10 mg/kg
Administration:Orally administration; 2-10 mg/kg; 4 weeks
Result:Had antihyperglycemic potential and improved insulin resistance.
体外研究：
Nepodin (Musizin) exhibits significant IC50 values that are 0.74 and 0.79 μg/ml against P. falciparum chloroquine-sensitive (3D7) and P. falciparum chloroquine-resistant (S20), respectively.
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