产品
编 号:F339173
分子式:C20H22N5NaO6S
分子量:483.47
产品类型
结构图
CAS No: 37091-65-9
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产品详情
生物活性:
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum.
体内研究:
Azlocillin (75 mg/kg) treatment increases the survival of neutropenic mice infected with Escherichia coli or Klebsiella pneumoniae.
体外研究:
Over 75% of the isolates of Pseudomonas aeruginosa are inhibited by Azlocillin at a concentration of 12.5 μg/mL. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98% and 71%, respectively, at a concentration of 12.5 μg/mL. Gram-positive cocci except penicillin G-resistant Staphylococcus aureus are susceptible to Azlocillin.