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编 号:F338786
分子式:C22H32Cl4N10
分子量:578.37
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5g
160
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生物活性:
Chlorhexidine dihydrochloride is an orally active antimicrobial agent. Chlorhexidine dihydrochloride can damage the bacteria cell wall, inhibit proliferation of S. sobrinus and induce DNA damage.

体内研究:
Chlorhexidine dihydrochloride (0.12% Chlorhexidine dihydrochloride 0.5 ml,口服,每天 2 次,共 8 天) 导致大鼠 DNA 损伤。Animal Model:Wistar rats
Dosage:0.5 ml of 0.12% chlorhexidine digluconate
Administration:Oral
Result:Observed significant increase of DNA damage in leukocytes and oral mucosal cells.

体外研究:
Chlorhexidine dihydrochloride (100-200 μM, 15-240 min) 可剂量依赖性地降低 S. aureus 活力。Chlorhexidine dihydrochloride (1.25-20 μM, 24 h) 可抑制人牙龈成纤维细胞的生长。
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