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编 号:F338521
分子式:C7H15N3O2
分子量:173.21
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生物活性:
L-NIO is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively. L-NIO induces a consistentfocal ischemic infarctin rats.

体内研究:
L-NIO (2.0 μmol, 3 days post-ischemia) causes focal cerebral ischemia in the adult rat brain.

体外研究:
L-NIO is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively.
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