产品
编 号:F337420
分子式:C13H16N2O
分子量:216.28
产品类型
结构图
CAS No: 36531-26-7
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产品详情
生物活性:
Oxantel (CP-14445), a m-oxyphenol derivative of Pyrantel (HY-12641), is a N-subtype AChR agonist. Oxantel is an anthelmintic, with excellent trichuricidal properties.
体内研究:
Oxantel (1-10 mg/kg; i.p.) displays a high activity against T. muris in vivo, with an EC50 of 4.71 mg/kg.Oxantel (10 mg/kg; i.p.) exhibits a worm burden reduction (WBR) of 92.5% and worm expulsion rate (WER) of 88.4% for T. muris.Animal Model:4 week-old female C57BL/10 mice and 3 week-old male
Dosage:1 mg/kg, 2.5 mg/kg, 5 mg/kg, 10 mg/kg
Administration:Intraperitoneal injection
Result:Inhibited T. muris in vivo.
体外研究:
Oxantel ( 0.015-600 μg/mL; 24-72 hours) reduces the viability of T. muris.