产品
编 号：F335973
分子式：C26H43NO5
分子量：449.62
分子式：C26H43NO5
分子量：449.62
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
304
In-stock
结构图
CAS No: 360-65-6
产品详情
生物活性：
Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.
体内研究：
Glycodeoxycholic Acid (11.20 mg/kg, 胆胰管注射) 对猕猴急性胰腺炎有诱导作用。Animal Model:Experimental macaque model
Dosage:11.20 mg/kg
Administration:injected along the biliopancreatic duct
Result:Increased the levels of Serum amylase and lipase.Elevated Blood pressure and heart rate.
体外研究：
Glycodeoxycholic Acid (200 μM, 24-48 h) 通过 STAT3 信号通路诱导肝癌细胞的干性和化疗耐药。Glycodeoxycholic Acid (50 μM, 预处理 1 h) 可消除 UCB 诱导的细胞色素 c 氧化酶抑制，并显著防止氧化应激、代谢改变和细胞死亡。
Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.
体内研究：
Glycodeoxycholic Acid (11.20 mg/kg, 胆胰管注射) 对猕猴急性胰腺炎有诱导作用。Animal Model:Experimental macaque model
Dosage:11.20 mg/kg
Administration:injected along the biliopancreatic duct
Result:Increased the levels of Serum amylase and lipase.Elevated Blood pressure and heart rate.
体外研究：
Glycodeoxycholic Acid (200 μM, 24-48 h) 通过 STAT3 信号通路诱导肝癌细胞的干性和化疗耐药。Glycodeoxycholic Acid (50 μM, 预处理 1 h) 可消除 UCB 诱导的细胞色素 c 氧化酶抑制，并显著防止氧化应激、代谢改变和细胞死亡。
产品资料
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