产品
编 号：F335964
分子式：C21H28O6
分子量：376.44
分子式：C21H28O6
分子量：376.44
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 36062-07-4
产品详情
生物活性：
Octahydrocurcumin is a hydrogenated derivatives of curcumin; metabolite of curcumin.IC50 value:Target: OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavenging were tetrahydro-, hexahydro-, and octahydrocurcumin with IC50 values of 10.0, 11.7, and 12.3 microM, respectively . curcumin and tetrahydrocurcumin significantly inhibited the release of prominent cytokines, including tumor necrosis factor α (TNF α) and interleukin 6 (IL 6); however, hexahydrocurcumin and octahydrocurcumin did not significantly alter cytokine release . Hydrogenated derivatives of curcumin exhibited stronger DPPH scavenging activity compared to curcumin and a reference antioxidant, trolox. The scavenging activity significantly decreased in the order THC>HHC=OHC>trolox>curcumin>Dmc>>>Bdmc .
Octahydrocurcumin is a hydrogenated derivatives of curcumin; metabolite of curcumin.IC50 value:Target: OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavenging were tetrahydro-, hexahydro-, and octahydrocurcumin with IC50 values of 10.0, 11.7, and 12.3 microM, respectively . curcumin and tetrahydrocurcumin significantly inhibited the release of prominent cytokines, including tumor necrosis factor α (TNF α) and interleukin 6 (IL 6); however, hexahydrocurcumin and octahydrocurcumin did not significantly alter cytokine release . Hydrogenated derivatives of curcumin exhibited stronger DPPH scavenging activity compared to curcumin and a reference antioxidant, trolox. The scavenging activity significantly decreased in the order THC>HHC=OHC>trolox>curcumin>Dmc>>>Bdmc .
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