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编 号:F335201
分子式:C34H46ClN3O10
分子量:692.2
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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生物活性:
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations.

体外研究:
Maytansine, at 6x10-8 M, irreversibly inhibits cell division in eggs of sea urchins and clams. Maytansine causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine inhibits in vitro polymerization of tubulin.
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