产品
编 号:F334938
分子式:C13H18ClNO2
分子量:255.74
产品类型
结构图
CAS No: 357399-43-0
联系客服
产品详情
生物活性:
Bupropion morpholinol (Hydroxy Bupropion) is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities.
体外研究:
Bupropion morpholinol is produced from Bupropion by the genetically polymorphic enzyme CYP2B6 in vivo.Bupropion morpholinol inhibits [3H]norepinephrine uptake with an IC50 of 1.7 μM.