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编 号:F334938
分子式:C13H18ClNO2
分子量:255.74
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1mg
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5mg
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生物活性:
Bupropion morpholinol (Hydroxy Bupropion) is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities.

体外研究:
Bupropion morpholinol is produced from Bupropion by the genetically polymorphic enzyme CYP2B6 in vivo.Bupropion morpholinol inhibits [3H]norepinephrine uptake with an IC50 of 1.7 μM.
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