产品
编 号：F004320
分子式：C84H137N29O26
分子量：1969.17
分子式：C84H137N29O26
分子量：1969.17
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规格
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CAS No: 100853-58-5
产品详情
生物活性：
PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors.
体外研究：
PKI(5-22)amide (1 μM; 1 min) fails to block CRF1?receptor (100 nM; 30 min) desensitization in Y-79 cells permeabilized with Streptolysin O (HY-135416).
PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors.
体外研究：
PKI(5-22)amide (1 μM; 1 min) fails to block CRF1?receptor (100 nM; 30 min) desensitization in Y-79 cells permeabilized with Streptolysin O (HY-135416).
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