产品
编 号：F334595
分子式：C19H15N3OS
分子量：333.41
分子式：C19H15N3OS
分子量：333.41
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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2mg
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5mg
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10mg
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结构图
CAS No: 356568-70-2
产品详情
生物活性：
Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1?μM for β-arrestin1 and 15.6?μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis.
体外研究：
Barbadin (4 h) treatment reduces cell viability and induces apoptosis.?Barbadin (2 h) treatment arrests breast cancer cells in G0/G1 phase.
Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1?μM for β-arrestin1 and 15.6?μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis.
体外研究：
Barbadin (4 h) treatment reduces cell viability and induces apoptosis.?Barbadin (2 h) treatment arrests breast cancer cells in G0/G1 phase.
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