产品
编 号:F334352
分子式:C16H17N3O7S2
分子量:427.45
产品类型
结构图
CAS No: 35607-66-0
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产品详情
生物活性:
Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria.
体内研究:
Cefoxitin (20 mg/kg; i.p.; daily; for 5 days) effectively kills B. burgdorferi in C3H/HeN mice model.Animal Model:Four-week-old female C3H/HeN mice
Dosage:20 mg/kg
Administration:Intraperitoneal injection, daily, for five consecutive days
Result:Had shown high efficacy killing B. burgdorferi in vivo.
体外研究:
Cefoxitin has good activity against Gram-positive bacteria. The MICs for several Gram-positive pathogens are in the range of 1-6 μg/mL.Cefoxitin exhibits high efficacy killing B. burgdorferi at concentration of 1.25 μM/mL.