产品
编 号:F038489
分子式:C41H28N6Na4O17S4
分子量:1096.91
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5mg
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生物活性:
NF110 is a P2X3 receptor antagonist (Ki = 36 nM) and inactive toward P2Y receptors stably expressed (IC50s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC50 = 527 nM) in rat dorsal root ganglia neurons.

体内研究:
NF110 shows potency at Endogenous P2X Receptors in Rat DRG Neurons, with a peak amplitude of 675 pA.

体外研究:
NF110 shows an activity in the human tumour cell line panel, with IC30 of 362.3 μM.NF110 inhibits HMGA2-DNA interactions with an IC50 of 0.87 μM.
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