产品
编 号:F333420
分子式:C20H26Cl2N2O6
分子量:461.34
产品类型
结构图
CAS No: 35369-53-0
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产品详情
生物活性:
HBED dihydrochloride is an orally active and hexadentate phenolic aminocarboxylate iron chelator. HBED refers to N, N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid, inducing iron excretion in primates. HBED dihydrochloride has the potential to be used as an alternative to desferriamine for iron chelation therapy.
体内研究:
HBED monohydrochloride dihydrate 在不同的给药方式下,产生的活性不同。HBED 以 81、162 和 324 μMol/kg 的剂量,口服给药后不会产生显著效果。而以 162 和 324 μMol/kg的剂量,在皮下给药后,提高了净铁排泄量。