产品
编 号:F333314
分子式:C22H20N2O2S
分子量:376.47
产品类型
结构图
CAS No: 353483-92-8
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产品详情
生物活性:
TQS is a α7 nicotinic acetylcholine receptor (nAChR) positive allosteric modulator. TQS can be used for the research of neuroinflammatory pain.
体内研究:
TQS (1 or 4 mg/kg; i.p.) reduces the expression of LPS-induced IκB mRNA, CD11b mRNA and regulates microglial morphological changes in the hippocampus.Animal Model:Male C57BL/6J mice
Dosage:1 or 4 mg/kg
Administration:I.p.
Result:Reduced the expression of LPS-induced IκB mRNA, CD11b mRNA and regulated microglial morphological changes in the hippocampus.