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编 号:F330675
分子式:C27H34N4O3
分子量:462.58
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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生物活性:
Fedovapagon (VA106483) is a selective and orally active vasopressin V2 receptor (V2R) agonist with an EC50 of 24 nM. Fedovapagon can be used in the research of nocturia.

体内研究:
Fedovapagon (1 mg/kg, oral administration) inhibits urine output with 81% inhibition rate in rats.Animal Model:Brattleboro rats
Dosage:1 mg/kg, 3 mg/kg
Administration:Oral administration
Result:Reduced urine volume with almost full inhibition of urine output for 2 h.Returned the urine to normal levels 5 h after dosing.
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