产品
编 号：F324009
分子式：C17H14O5
分子量：298.29
分子式：C17H14O5
分子量：298.29
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
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询价
结构图
CAS No: 33458-93-4
产品详情
生物活性：
AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor.
体内研究：
AH 6809 (5 mg/kg; i.p.) decreases TsV-induced mortality, PGE2 and IL-1β production and neutrophil infiltration in the lungs of mice.
体外研究：
AH 6809 (1?μM; 30 min) inhibits T. serrulatus venom (TsV)-induced and PGE2-amplified IL-1β and cAMP production in macrophages.AH 6809 (30-300 μM) antagonizes the anti-aggregatory activity of PGD2 in whole blood, with an apparent pA2 of 5.35.
AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor.
体内研究：
AH 6809 (5 mg/kg; i.p.) decreases TsV-induced mortality, PGE2 and IL-1β production and neutrophil infiltration in the lungs of mice.
体外研究：
AH 6809 (1?μM; 30 min) inhibits T. serrulatus venom (TsV)-induced and PGE2-amplified IL-1β and cAMP production in macrophages.AH 6809 (30-300 μM) antagonizes the anti-aggregatory activity of PGD2 in whole blood, with an apparent pA2 of 5.35.
产品资料
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