产品
编 号：F323780
分子式：C21H32ClN5O2
分子量：421.96
分子式：C21H32ClN5O2
分子量：421.96
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
400
In-stock
结构图
CAS No: 33386-08-2
产品详情
生物活性：
Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research.
体内研究：
Buspirone hydrochloride (1-5 mg/kg；ip 和 ig；5 天；C57BL/6N 小鼠) 减少焦虑/抑郁行为。Buspirone hydrochloride (1-5 mg/kg；ip 和 ig；持续 5 天；C57BL/6N 小鼠) 恢复肠道微生物群中 IS 转移的 β 多样性。Animal Model:Male C57BL/6N mice
Dosage:1 and 5 mg/kg
Administration:Oral gavage and intraperitoneal injection; for 5 days
Result:Reduced TNF-α expression and NF-κB+/Iba1+ cell population in the hippocampus and myeloperoxidase activity and NF-κB+/CD11c+ cell population in the colon.
Animal Model:Male C57BL/6N mice
Dosage:1 and 5 mg/kg
Administration:Oral gavage and intraperitoneal injection; for 5 days
Result:Reduced the IS- or EC-induced gut Proteobacteria population.
体外研究：
Buspirone hydrochloride (0-400 μg/mL；6 hours) 对淋巴细胞有细胞毒作用。Buspirone hydrochloride (0-180 μg/mL；0-3 小时；淋巴细胞) 诱导 ROS 形成、MMP 崩溃、脂质过氧化、溶酶体损伤和谷胱甘肽二硫化物 (GSSG) 升高。
Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research.
体内研究：
Buspirone hydrochloride (1-5 mg/kg；ip 和 ig；5 天；C57BL/6N 小鼠) 减少焦虑/抑郁行为。Buspirone hydrochloride (1-5 mg/kg；ip 和 ig；持续 5 天；C57BL/6N 小鼠) 恢复肠道微生物群中 IS 转移的 β 多样性。Animal Model:Male C57BL/6N mice
Dosage:1 and 5 mg/kg
Administration:Oral gavage and intraperitoneal injection; for 5 days
Result:Reduced TNF-α expression and NF-κB+/Iba1+ cell population in the hippocampus and myeloperoxidase activity and NF-κB+/CD11c+ cell population in the colon.
Animal Model:Male C57BL/6N mice
Dosage:1 and 5 mg/kg
Administration:Oral gavage and intraperitoneal injection; for 5 days
Result:Reduced the IS- or EC-induced gut Proteobacteria population.
体外研究：
Buspirone hydrochloride (0-400 μg/mL；6 hours) 对淋巴细胞有细胞毒作用。Buspirone hydrochloride (0-180 μg/mL；0-3 小时；淋巴细胞) 诱导 ROS 形成、MMP 崩溃、脂质过氧化、溶酶体损伤和谷胱甘肽二硫化物 (GSSG) 升高。
产品资料
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