产品
编 号:F321246
分子式:C5H6O5
分子量:146.1
产品类型
结构图
CAS No: 328-50-7
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产品详情
生物活性:
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM).
体外研究:
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning.2-Ketoglutaric acid acts as precursor for the synthesis of amino acids and nucleotides.