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编 号:F320559
分子式:C22H27ClN4O2
分子量:414.93
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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生物活性:
SU11652 is a potent receptor tyrosine kinase (RTK) inhibitor. SU11652 also inhibits several members of the split kinase family of RTKs, including VEGFR, FGFR, PDGFR, and Kit. SU11652 can be uesd for spontaneous cancers expressing Kit mutations research.

体外研究:
SU11652 (0-1 μM, 0-72 h) inhibits the growth of mast cell lines expressing mutant Kit.SU11652 (0-1 μM, 0-72 h) induces cell cycle arrest followed by apoptosis in cell lines expressing mutant Kit.
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