产品
编 号:F319434
分子式:C6H12Br2N4S
分子量:332.06
产品类型
结构图
CAS No: 32385-58-3
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产品详情
生物活性:
Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively. Imetit mimics histamine effect in triggering a shape change in eosinophils (EC50=25 nM).
体内研究:
Imetit dihydrobromide (2.5-10 mg/kg; i.p.) reduces the licking response induced by Apomorphine.Animal Model:Male Sprague-Dawley rats
Dosage:2.5, 5, 10 mg/kg
Administration:i.p. (30 min before Apomorphine)
Result:Reduced the licking response induced by Apomorphine.