产品
编 号:F319424
分子式:C16H14O4
分子量:270.28
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1mg
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5mg
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10mg
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生物活性:
Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of agents.

体外研究:
Medicarpin (90 μM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 μM for P388 and P388/DOX cells).
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