产品
编 号：F318754
分子式：C10H12N2O
分子量：176.22
分子式：C10H12N2O
分子量：176.22
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CAS No: 32162-64-4
产品详情
生物活性：
R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs.
体内研究：
R-(+)-Cotinine (0.3-10 mg/kg; a single i.p.) enhances the effects of a subthreshold dose of Donepezil (0.5 mg/kg) on novel object recognition (NOR) performance.
体外研究：
R-(+)-Cotinine (1 μM) significantly enhances the Ach (40 μM)-evoked current in human α7 nAChRs.
R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs.
体内研究：
R-(+)-Cotinine (0.3-10 mg/kg; a single i.p.) enhances the effects of a subthreshold dose of Donepezil (0.5 mg/kg) on novel object recognition (NOR) performance.
体外研究：
R-(+)-Cotinine (1 μM) significantly enhances the Ach (40 μM)-evoked current in human α7 nAChRs.
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