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编 号:F316981
分子式:C4H12N2O6
分子量:184.15
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生物活性:
L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications.

体内研究:
L-Tartaric acid (80-240 mg/kg; 口服给药; 单剂量) 在 L-NAME (60 mg/kg) 诱导的高血压小鼠中可以降低小鼠的血压。Animal Model:Hypertensive Wistar rat model
Dosage:80 mg/kg, 240 mg/kg
Administration:Oral gavage (p.o.); Single dose. After L-NAME treatment (60.mg/kg; p.o.)
Result:Reduced systolic blood pressure (SABP) and mild blood pressure (mid-BP) in rats at a dose of 240mg/kg, but had no effect on mean artery pressure, diastolic blood pressure, pulse pressure level, and heart rate.

体外研究:
L-Tartaric acid (1.66-6.64 mM) 显著降低 NEP 和 KCL 诱导的主动脉环血管收缩,EC50 分别为 4.119 mM 和 4.00 mM。
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