产品
编 号:F316594
分子式:C23H28O12
分子量:496.46
产品类型
结构图
CAS No: 31528-44-6
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产品详情
生物活性:
Mycophenolic acid glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic acid glucuronide shows anti-tumor activity and can be used in adenocarcinoma research.
体内研究:
Mycophenolic acid glucuronide (intraperitoneal injection; 6 mg/mouse; once two days; 6 d) treatment reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model.Animal Model:Swiss albino strain mouse implanted with Ehrlich ascites tumor cells
Dosage:6 mg/mouse
Administration:Intraperitoneal injection; 6 mg/mouse; once two days; 6 d
Result:Showed 76.8% tumor inhibition compared to the untreated control.
体外研究:
Mycophenolic acid glucuronide shows weak IMP dehydrogenase (IMPDH) type II inhibition with an IC50 of 3.3 mg/L.