产品
编 号:F316165
分子式:C34H24N6Na4O14S4
分子量:960.81
产品类型
结构图
CAS No: 314-13-6
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产品详情
生物活性:
Evans Blue (Direct Blue 53) is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor. Evans Blue has a strong affinity towards serum albumin, making it a high molecular weight protein tracer. Evans Blue is also used to study BBB (blood-brain barrier) permeability.
体内研究:
胶原酶注射产生脑出血后,Evans Blue(2% 溶液;4 mL/kg)染色剂在小鼠脑中累积的量与染色剂施用途径无关。Animal Model:CD-1 mice bearing intracerebral hemorrhage (ICH)
Dosage:2% solution; 4 mL/kg
Administration:Jugular vein or intraperitoneal injection; once
Result:Showed the amount of stain accumulated in the brains.
体外研究:
Evans Blue 是一种双偶氮染料,是一种非渗透染料。在质膜受损的情况下,Evans Blue 进入细胞质和细胞核,从而将它们染成蓝色。Evans Blue 可用于检查细胞活力。