产品
编 号:F036668
分子式:C9H19BrO4
分子量:271.15
产品类型
结构图
CAS No: 110429-45-3
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产品详情
生物活性:
m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
体外研究:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.