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编 号:F314921
分子式:C19H17Cl2N3O5S
分子量:470.33
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生物活性:
Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus.

体内研究:
Dicloxacillin exhibits therapeutic activity in murine peritonitis-sepsis model and all the mice are survivied.Animal Model:Female outbred Swiss Webster mice (Murine peritonitis-sepsis model).
Dosage:125 mg/kg.
Administration:IV injection, single doses.
Result:All the mice survived.

体外研究:
Dicloxacillin exhibits EC50 values of 0.06 and 0.50 mg/L in ATCC 25923 and E19977, respectively. Dicloxacillin exhibits MIC values of 0.125 and 0.5 mg/L in ATCC 25923 and E19977 with pH 7.4, respectively.
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